Atomic and cellular impacts  of the

Fragile-X Mental Retardation Protein modifications by SUMO

Fragile-X mental retardation protein, SUMO,

dynamics of multiprotein complexes ,

structural modélisation

Modeling the mechanical feedback of adipogenesis

Adipose tissue, adipogenesis, mechanical force,

mechanotransduction, mathematical modeling

Détection, classification and characterization of mitochondrial networks :

application to Alzheimer disease and Cancer

Identification of inhibitors disrupting MITF interactions with DNA

Anticancer drugs, Small G protein, invasion,

Biochemistry, chemical synthesis, molecule screening

Development of molecules for

therapy against chemoresistant blood diseases

Blood diseases, Myelodysplastic syndromes,

resistance, inhibitors, anticancer drugs

Identification of new generation

immunostimulatory and antimicrobial components

Parasite, Leishmaniose, natural components,

immunostimulation

Transfert proteins, lipid gradient, in vitro assays, distance,

microfluidics

Single cell, RNASeq, big data, machine learning,

gene network, biostatistics,

deconvolution, airway epithelium diseases